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The Oncologist, Vol. 4, No. 4, 332-339, August 1999
© 1999 AlphaMed Press

Fundamentals of Cancer Medicine

Apoptosis

Lyonel G. Israels, Esther D. Israels

University of Manitoba, Manitoba Cancer Treatment and Research Foundation, Manitoba, Canada

Correspondence: Lyonel G. Israels, M.D., Department of Medicine, University of Manitoba, 100 Olivia Street, Winnipeg, Canada R3E 0V9. Telephone: 204-787-2246; Fax: 204-787-1345; e-mail: lisraels{at}cc.umanitoba.ca

Mechanisms in Hematology is a book with an accompanying interactive CD-ROM designed to assemble basic concepts that underlie clinical understanding and progress. It is presented as a concise text with a series of diagrams that distill diffuse information into a compact form. The interactive CD, in particular, brings many of the processes "to life" as details of the more complex pathways are conveyed in clear visual images. The text begins with the basic molecular biology that underlies hematological and oncological physiology/pathology—cell signaling, adhesion molecules, and apoptosis. This is followed by sections, among others, on hematopoiesis, iron, B12, and folate metabolism, neutrophil function, immunoproteins, chemotherapy, and coagulation. With the permission of the authors and publisher, has reproduced the section on apoptosis, which we think our readers will enjoy.




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